ARL2BP antibody

Catalog No. ABIN7253101

This anti-ARL2BP antibody is a Rabbit Polyclonal antibody detecting ARL2BP in ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for ARL2BP antibody (ABIN7253101)

Target: ARL2BP (ADP-Ribosylation Factor-Like 2 Binding Protein (ARL2BP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL2BP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ARL2BP Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human ARL2BP

Isotype: IgG

Application Details

Application Notes: IHC 1:20-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARL2BP

Target: ARL2BP (ADP-Ribosylation Factor-Like 2 Binding Protein (ARL2BP))

Alternative Name: ARL2BP

Background: ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.ARL2BP (ADP Ribosylation Factor Like GTPase 2 Binding Protein) is a Protein Coding gene. Diseases associated with ARL2BP include Retinitis Pigmentosa With Or Without Situs Inversus and Arl2bp-Related Retinitis Pigmentosa. Among its related pathways are Integration of energy metabolism and Metabolism. GO annotations related to this gene include transcription coactivator activity and GTPase regulator activity.

UniProt: Q9Y2Y0

Pathways: Maintenance of Protein Location