SORD antibody

Catalog No. ABIN7254136

This anti-SORD antibody is a Rabbit Polyclonal antibody detecting SORD in IHC and ELISA. Suitable for Human and Mouse.

Quick Overview for SORD antibody (ABIN7254136)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORD antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-SORD Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human SORD

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD

Background: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

UniProt: Q00796