PPM1K antibody

Catalog No. ABIN7254154

The Rabbit Polyclonal anti-PPM1K antibody (ABIN7254154) specifically detects PPM1K in ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for PPM1K antibody (ABIN7254154)

Target: PPM1K (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1K (PPM1K))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1K antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PPM1K Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PPM1K

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPM1K

Target: PPM1K (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1K (PPM1K))

Alternative Name: PPM1K

Background: This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.PPM1K (Protein Phosphatase, Mg2+/Mn2+ Dependent 1K) is a Protein Coding gene. Diseases associated with PPM1K include Maple Syrup Urine Disease, Mild Variant and Intermediate Maple Syrup Urine Disease. Among its related pathways are Valine, leucine and isoleucine degradation and Viral mRNA Translation. GO annotations related to this gene include protein serine/threonine phosphatase activity. An important paralog of this gene is PPM1E.

UniProt: Q8N3J5