PSCA antibody

Catalog No. ABIN7254328

This Rabbit Polyclonal antibody specifically detects PSCA in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for PSCA antibody (ABIN7254328)

Target: PSCA (Prostate Stem Cell Antigen (PSCA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSCA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PSCA Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human PSCA

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSCA

Target: PSCA (Prostate Stem Cell Antigen (PSCA))

Alternative Name: PSCA

Background: PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40 % of primary prostate cancers and in as many as 100 % of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 13 kDa

UniProt: O43653