×
For best experience we recommend to activate Javascript in your browser.
CDKN1B antibody
CDKN1B
Reactivity: Human, Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDKN1B Antibody
(hide)
Target
See all CDKN1B Antibodies
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Reactivity
All reactivities for CDKN1B antibodies
Human, Mouse, Rat
Host
All hosts for CDKN1B antibodies
Rabbit
Clonality
All clonalities for CDKN1B antibodies
Polyclonal
Conjugate
All conjugates for CDKN1B antibodies
This CDKN1B antibody is un-conjugated
Application
All applications for CDKN1B antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human CDKN1B (NP_004055.1).
Isotype
IgG
Top Product
Discover our top product CDKN1B Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
IHC 1:50-1:200 IF 1:20-1:50
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for CDKN1B
(hide)
Target
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Alternative Name
CDKN1B (CDKN1B Products )
Background
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
Gene ID
1027
UniProt
P46527
Pathways
Cell Division Cycle , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Negative Regulation of Hormone Secretion , Sensory Perception of Sound , Mitotic G1-G1/S Phases , DNA Replication , Positive Regulation of Endopeptidase Activity , Synthesis of DNA , Autophagy
Recently viewed
(hide)