RIC8A antibody
Quick Overview for RIC8A antibody (ABIN7007364)
Target
See all RIC8A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein of human RIC8A (NP_001273063.1).
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Isotype
- IgG
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anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 462-534) antibody
RIC8A Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1H6 unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (C-Term) antibodyRIC8A Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 362-531) antibodyRIC8A Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 362-531) antibodyRIC8A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) antibodyRIC8A Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 244-272) antibodyRIC8A Reactivity: Human WB Host: Rabbit Polyclonal RB37066 unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (C-Term) antibodyVerified RIC8A Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 143-192) antibodyRIC8A Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (N-Term) antibodyRIC8A Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
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Alternative Name
- RIC8A
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Background
- Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
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Molecular Weight
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Observed_MW: 60 kDa
Calculated_MW: 58 kDa/59 kDa/60 kDa
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Gene ID
- 60626
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UniProt
- Q9NPQ8
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization
Target
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