×
For best experience we recommend to activate Javascript in your browser.
RIC8A antibody (AA 244-272)
RIC8A
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB37066
unconjugated
Product Details anti-RIC8A Antibody
(hide)
Target
See all RIC8A Antibodies
RIC8A
(Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
Binding Specificity
All epitopes for RIC8A antibodies
AA 244-272
Reactivity
All reactivities for RIC8A antibodies
Human
Host
All hosts for RIC8A antibodies
Rabbit
Clonality
All clonalities for RIC8A antibodies
Polyclonal
Conjugate
All conjugates for RIC8A antibodies
This RIC8A antibody is un-conjugated
Application
All applications for RIC8A antibodies
Western Blotting (WB)
Predicted Reactivity
Pr
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RIC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-272 amino acids from the Central region of human RIC8A.
Clone
RB37066
Isotype
Ig Fraction
Top Product
Discover our top product RIC8A Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
RIC8A Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Expiry Date
6 months
Target Details for RIC8A
(hide)
Target
RIC8A
(Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
Alternative Name
RIC8A (RIC8A Products )
Synonyms
RIC8 antibody, AI114950 antibody, RIC-8 antibody, Ric8a antibody, Ric-8A antibody, Ric8 antibody, ric-8 antibody, ric8 antibody, synembryn antibody, xtric-8 antibody, zgc:92294 antibody, Syn antibody, ric8a antibody, ric8ab antibody, CG15797 antibody, DmRic8 antibody, Dmel\\CG15797 antibody, Ric-8 antibody, l(1)G0397 antibody, ric-8a antibody, ricc8aa antibody, fj97c10 antibody, synbl antibody, wu:fj97c10 antibody, RIC8 guanine nucleotide exchange factor A antibody, microRNA 6743 antibody, synembryn-A antibody, RIC8 guanine nucleotide exchange factor A L homeolog antibody, CG15797 gene product from transcript CG15797-RB antibody, synembryn antibody, RIC8 guanine nucleotide exchange factor A S homeolog antibody, Synembryn antibody, RIC8 guanine nucleotide exchange factor B antibody, RIC8A antibody, Ric8a antibody, ric8a antibody, MIR6743 antibody, Tsp_08768 antibody, ric8a.L antibody, LOC411841 antibody, ric8a.S antibody, ric-8 antibody, ric8b antibody
Background
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
Molecular Weight
59710
Gene ID
60626
NCBI Accession
NP_068751
UniProt
Q9NPQ8
Pathways
Regulation of G-Protein Coupled Receptor Protein Signaling , Feeding Behaviour , Asymmetric Protein Localization
Recently viewed
(hide)