SART3 antibody
Quick Overview for SART3 antibody (ABIN7255932)
Target
See all SART3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein of human SART3 (NP_055521.1).
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
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Alternative Name
- SART3
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Background
- The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
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Molecular Weight
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Observed_MW: 130 kDa
Calculated_MW: 13 kDa/41 kDa/105 kDa/109 kDa
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Gene ID
- 9733
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UniProt
- Q15020
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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