PDE4D antibody
Quick Overview for PDE4D antibody (ABIN7257497)
Target
See all PDE4D AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein of human PDE4D (NP_001184152.1).
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000 IF 1:20-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
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Alternative Name
- PDE4D
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Background
- This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
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Molecular Weight
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Observed_MW: 110 kDa
Calculated_MW: 23-24 kDa/57-91 kDa
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Gene ID
- 5144
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UniProt
- Q08499
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Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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