PON2 antibody

Catalog No. ABIN7008586

The Rabbit Polyclonal anti-PON2 antibody (ABIN7008586) specifically detects PON2 in IHC and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for PON2 antibody (ABIN7008586)

Target: PON2 (Paraoxonase 2 (PON2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PON2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PON2 (NP_000296.2).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PON2

Target: PON2 (Paraoxonase 2 (PON2))

Alternative Name: PON2

Background: This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene ID: 5445

UniProt: Q15165