Dystrophin antibody

Catalog No. ABIN7008615

The Rabbit Polyclonal anti-Dystrophin antibody has been validated for IHC, WB and IF. It is suitable to detect Dystrophin in samples from Human, Mouse and Rat.

Quick Overview for Dystrophin antibody (ABIN7008615)

Target: Dystrophin (DMD)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystrophin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Dystrophin Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human DMD (NP_004007.1).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Dystrophin

Target: Dystrophin (DMD)

Alternative Name: DMD

Background: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.

Molecular Weight:

Observed_MW: 427 kDa

Calculated_MW: 57-72 kDa/271 kDa/425-426 kDa

Gene ID: 1756

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development