MKL1 antibody

Catalog No. ABIN7257724

This Rabbit Polyclonal antibody specifically detects MKL1 in WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MKL1 antibody (ABIN7257724)

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MKL1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MKL1 (NP_065882.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MKL1

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Alternative Name: MKL1

Background: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 150 kDa

Calculated_MW: 98 kDa

Gene ID: 57591

UniProt: Q969V6