MZB1 antibody

Catalog No. ABIN7257892

The Rabbit Polyclonal anti-MZB1 antibody is suitable to detect MZB1 in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for MZB1 antibody (ABIN7257892)

Target: MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MZB1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-MZB1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MZB1 (NP_057543.2).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MZB1

Target: MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))

Alternative Name: MZB1

Background: Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.

Gene ID: 51237

UniProt: Q8WU39

Pathways: Production of Molecular Mediator of Immune Response