TSG101 antibody
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- Target See all TSG101 Antibodies
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TSG101 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human TSG101 (NP_006283.1).
- Isotype
- IgG
- Top Product
- Discover our top product TSG101 Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
- Alternative Name
- TSG101 (TSG101 Products)
- Background
- The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
- Molecular Weight
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Observed_MW: 44 kDa
Calculated_MW: 31 kDa/43 kDa
- Gene ID
- 7251
- UniProt
- Q99816
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