RGS4 antibody

Catalog No. ABIN7259747

The Rabbit Polyclonal anti-RGS4 antibody (ABIN7259747) specifically detects RGS4 in WB and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RGS4 antibody (ABIN7259747)

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RGS4 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human RGS4 (NP_005604.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RGS4

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Alternative Name: RGS4

Background: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight:

Observed_MW: 30 kDa

Calculated_MW: 10 kDa/21 kDa/23 kDa/33 kDa

Gene ID: 5999

UniProt: P49798

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling