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Importin 5 antibody

IPO5 Reactivity: Human, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7260031
  • Target See all Importin 5 (IPO5) Antibodies
    Importin 5 (IPO5)
    Reactivity
    • 26
    • 26
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 37
    • 4
    Rabbit
    Clonality
    • 39
    • 2
    Polyclonal
    Conjugate
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Importin 5 antibody is un-conjugated
    Application
    • 13
    • 13
    • 11
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human IPO5 (NP_002262.3).
    Isotype
    IgG
    Top Product
    Discover our top product IPO5 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Importin 5 (IPO5)
    Alternative Name
    IPO5 (IPO5 Products)
    Synonyms
    IPO5 antibody, RANBP5 antibody, IMB3 antibody, KPNB3 antibody, Pse1 antibody, imp5 antibody, 1110011C18Rik antibody, 5730478E03Rik antibody, AA409333 antibody, C76941 antibody, Kpnb3 antibody, Ranbp5 antibody, importin 5 antibody, IPO5 antibody, Ipo5 antibody
    Background
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
    Molecular Weight

    Observed_MW: 124 kDa

    Calculated_MW: 116 kDa/123 kDa/125 kDa

    Gene ID
    3843
    UniProt
    O00410
    Pathways
    Protein targeting to Nucleus
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