DNMT3L antibody
Quick Overview for DNMT3L antibody (ABIN7260352)
Target
See all DNMT3L (TRDMT1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein of human DNMT3L (NP_787063.1).
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Isotype
- IgG
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anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 1-386) antibody
TRDMT1 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 147-386) antibodyTRDMT1 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 2D10H11 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (Internal Region) antibodyTRDMT1 Reactivity: Human, Mouse WB, ELISA, IHC, IF, IP, ICC, ChIP Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 357-388), (C-Term) antibodyTRDMT1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB02219 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 1-234) antibodyTRDMT1 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 389-421) antibodyTRDMT1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB2393 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 1-386) antibodyTRDMT1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 150-175) antibodyTRDMT1 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 383-417), (C-Term) antibodyTRDMT1 Reactivity: Mouse WB Host: Rabbit Polyclonal RB50995 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 151-386) antibodyTRDMT1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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Application Notes
- IHC 1:50-1:200 IF 1:20-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
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Alternative Name
- DNMT3L
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Background
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Gene ID
- 29947
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UniProt
- Q9UJW3
Target
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