APLP1 antibody

Catalog No. ABIN7260605

This Rabbit Polyclonal antibody specifically detects APLP1 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for APLP1 antibody (ABIN7260605)

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-APLP1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human APLP1 (NP_005157.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for APLP1

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Alternative Name: APLP1

Background: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight:

Observed_MW: 65-70 kDa

Calculated_MW: 72 kDa

Gene ID: 333

UniProt: P51693

Pathways: cAMP Metabolic Process