COX6A1 antibody

Catalog No. ABIN7260863

The Rabbit Polyclonal anti-COX6A1 antibody is suitable to detect COX6A1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and IF.

Quick Overview for COX6A1 antibody (ABIN7260863)

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-COX6A1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human COX6A1 (NP_004364.2).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000 IHC 1:20-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COX6A1

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Alternative Name: COX6A1

Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66 % amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.

Molecular Weight:

Observed_MW: 12 kDa

Calculated_MW: 12 kDa

Gene ID: 1337

UniProt: P12074