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NBR1 antibody

NBR1 Reactivity: Human, Mouse, Rat, Monkey IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7010379
  • Target See all NBR1 Antibodies
    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
    Reactivity
    • 18
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Monkey
    Host
    • 12
    • 8
    Rabbit
    Clonality
    • 15
    • 5
    Polyclonal
    Conjugate
    • 20
    This NBR1 antibody is un-conjugated
    Application
    • 17
    • 9
    • 5
    • 4
    • 3
    • 3
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human NBR1
    Isotype
    IgG
    Top Product
    Discover our top product NBR1 Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
    Alternative Name
    NBR1 (NBR1 Products)
    Synonyms
    fa99f08 antibody, wu:fa99f08 antibody, MGC69008 antibody, NBR1 antibody, 1A1-3B antibody, M17S2 antibody, mKIAA0049 antibody, Ca125 antibody, RGD1311421 antibody, neighbor of brca1 gene 1a antibody, neighbor of BRCA1 gene 1 L homeolog antibody, NBR1, autophagy cargo receptor antibody, neighbor of Brca1 gene 1 antibody, nbr1a antibody, nbr1.L antibody, NBR1 antibody, Nbr1 antibody
    Background
    The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
    Gene ID
    4077
    UniProt
    Q14596
    Pathways
    Autophagy
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