RRM2 antibody

Catalog No. ABIN7010535

This Rabbit Polyclonal antibody specifically detects RRM2 in WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RRM2 antibody (ABIN7010535)

Target: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RRM2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human RRM2 (NP_001025.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RRM2

Target: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Alternative Name: RRM2

Background: This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.

Molecular Weight:

Observed_MW: 45 kDa

Calculated_MW: 44 kDa/51 kDa

Gene ID: 6241

UniProt: P31350

Pathways: Mitotic G1-G1/S Phases