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DLD antibody

The Rabbit Polyclonal anti-DLD antibody has been validated for WB and IHC. It is suitable to detect DLD in samples from Human and Mouse.
Catalog No. ABIN7010617

Quick Overview for DLD antibody (ABIN7010617)

Target

See all DLD Antibodies
DLD (Dihydrolipoamide Dehydrogenase (DLD))

Reactivity

  • 46
  • 27
  • 27
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 53
  • 6
Rabbit

Clonality

  • 49
  • 10
Polyclonal

Conjugate

  • 37
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DLD antibody is un-conjugated

Application

  • 54
  • 23
  • 23
  • 14
  • 13
  • 10
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Characteristics

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogen

    Recombinant fusion protein of human DLD (NP_000099.2).

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000 IHC 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    DLD (Dihydrolipoamide Dehydrogenase (DLD))

    Alternative Name

    DLD

    Background

    This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.

    Molecular Weight

    Observed_MW: 55 kDa

    Calculated_MW: 43 kDa/49 kDa/54 kDa

    Gene ID

    1738

    UniProt

    P09622

    Pathways

    Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
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