TET2 antibody

Catalog No. ABIN7261632

The Rabbit Polyclonal anti-TET2 antibody is suitable to detect TET2 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for TET2 antibody (ABIN7261632)

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TET2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TET2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TET2 (NP_001120680.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:100-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TET2

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Alternative Name: TET2

Background: The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 300 kDa

Calculated_MW: 130 kDa/133 kDa/223 kDa

Gene ID: 54790

UniProt: Q6N021

Pathways: Warburg Effect