HuC/ELAVL3 antibody

Catalog No. ABIN7261946

This anti-HuC/ELAVL3 antibody is a Rabbit Polyclonal antibody detecting HuC/ELAVL3 in WB, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for HuC/ELAVL3 antibody (ABIN7261946)

Target: HuC/ELAVL3 (ELAVL3) (ELAV-Like 3 (ELAVL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HuC/ELAVL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HuC/ELAVL3 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human ELAVL3 (NP_001411.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HuC/ELAVL3

Target: HuC/ELAVL3 (ELAVL3) (ELAV-Like 3 (ELAVL3))

Alternative Name: ELAVL3

Background: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 37 kDa

Calculated_MW: 38 kDa/39 kDa

Gene ID: 1995

UniProt: Q14576