GAMT antibody

Catalog No. ABIN7262471

The Rabbit Polyclonal anti-GAMT antibody (ABIN7262471) specifically detects GAMT in IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GAMT antibody (ABIN7262471)

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAMT antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-GAMT Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GAMT (NP_000147.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GAMT

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Alternative Name: GAMT

Background: The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

Gene ID: 2593

UniProt: Q14353