NR2C1 antibody

Catalog No. ABIN7262563

This Rabbit Polyclonal antibody specifically detects NR2C1 in WB and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for NR2C1 antibody (ABIN7262563)

Target: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2C1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-NR2C1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human NR2C1 (NP_003288.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NR2C1

Target: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Alternative Name: NR2C1

Background: This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.

Molecular Weight:

Observed_MW: 75 kDa

Calculated_MW: 51 kDa/53 kDa/67 kDa

Gene ID: 7181

UniProt: P13056

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway