RAMP3 antibody

Catalog No. ABIN7262613

This anti-RAMP3 antibody is a Rabbit Polyclonal antibody detecting RAMP3 in IF. Suitable for Human, Mouse and Rat.

Quick Overview for RAMP3 antibody (ABIN7262613)

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAMP3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-RAMP3 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human RAMP3 (NP_005847.1).

Isotype: IgG

Application Details

Application Notes: IF 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RAMP3

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Alternative Name: RAMP3

Background: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

Gene ID: 10268

UniProt: O60896

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling