SECISBP2 antibody

Catalog No. ABIN7262647

The Rabbit Polyclonal anti-SECISBP2 antibody is suitable to detect SECISBP2 in samples from Human and Mouse. It has been validated for IF and IHC.

Quick Overview for SECISBP2 antibody (ABIN7262647)

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SECISBP2 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-SECISBP2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SECISBP2 (NP_076982.3).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SECISBP2

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Alternative Name: SECISBP2

Background: The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.

Gene ID: 79048

UniProt: Q96T21