Caveolin 3 antibody

Catalog No. ABIN7264133

This anti-Caveolin 3 antibody is a Rabbit Polyclonal antibody detecting Caveolin 3 in IHC. Suitable for Human and Mouse.

Quick Overview for Caveolin 3 antibody (ABIN7264133)

Target: Caveolin 3 (CAV3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Caveolin 3 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CAV3 (NP_001225.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Caveolin 3

Target: Caveolin 3 (CAV3)

Alternative Name: CAV3

Background: This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Gene ID: 859

UniProt: P56539

Pathways: Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity