METTL7A antibody

Catalog No. ABIN7264251

This anti-METTL7A antibody is a Rabbit Polyclonal antibody detecting METTL7A in WB and IHC. Suitable for Human and Rat.

Quick Overview for METTL7A antibody (ABIN7264251)

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL7A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-METTL7A Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human METTL7A (NP_054752.3).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for METTL7A

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Alternative Name: METTL7A

Background: METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1,100 genes, chromosome 12 comprises nearly 4.5 % of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.

Molecular Weight:

Observed_MW: 28 kDa

Calculated_MW: 28 kDa

Gene ID: 25840

UniProt: Q9H8H3