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Src Family (pTyr416) antibody

The Rabbit Polyclonal anti-Src Family antibody (ABIN7265222) specifically detects Src Family in WB. The antibody is reactive with Human, Mouse and Rat samples.
Catalog No. ABIN7265222
$708.00
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Quick Overview for Src Family (pTyr416) antibody (ABIN7265222)

Target

Src Family

Reactivity

Human, Mouse, Rat

Host

  • 10
Rabbit

Clonality

  • 9
  • 1
Polyclonal

Conjugate

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Un-conjugated

Application

  • 10
  • 9
  • 9
Western Blotting (WB)
  • Binding Specificity

    pTyr416

    Characteristics

    Phosphorylated antibody

    Purification

    Affinity purification

    Immunogen

    A phospho specific peptide corresponding to residues surrounding Y416 of human SRC Family

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Src Family

    Background

    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

    Molecular Weight

    Observed_MW: 60 kDa

    Calculated_MW: 59 kDa/60 kDa

    Gene ID

    6714

    UniProt

    P12931
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