IKK-alpha /IKK-beta antibody (pSer176, pSer180)

Catalog No. ABIN7265254

This Rabbit Polyclonal antibody specifically detects IKK-alpha /IKK-beta in WB. It exhibits reactivity toward Mouse and Human.

Quick Overview for IKK-alpha /IKK-beta antibody (pSer176, pSer180) (ABIN7265254)

Target: IKK-alpha /IKK-beta

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKK-alpha /IKK-beta antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IKK-alpha /IKK-beta Antibody

Binding Specificity: pSer176, pSer180

Characteristics: Phosphorylated antibody

Purification: Affinity purification

Immunogen: A synthetic phosphorylated peptide around S176 of human IKK-alpha (NP_001269.3).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IKK-alpha /IKK-beta

Target: IKK-alpha /IKK-beta

Alternative Name: IKKalpha/beta

Background: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Molecular Weight:

Observed_MW: 85 kDa

Calculated_MW: 84 kDa/29 kDa/79 kDa/85 kDa/86 kDa

Gene ID: 1147, 3551

UniProt: O15111, O14920