PRKAA1 antibody (pSer485)
Quick Overview for PRKAA1 antibody (pSer485) (ABIN7265282)
Target
See all PRKAA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer485
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Characteristics
- Phosphorylated antibody
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Purification
- Affinity purification
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Immunogen
- A phospho specific peptide corresponding to residues surrounding S485 of human PRKAA1
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
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Alternative Name
- AMPKalpha1
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Background
- The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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Molecular Weight
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Observed_MW: 56 kDa
Calculated_MW: 64 kDa/65 kDa
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Gene ID
- 5562
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UniProt
- Q13131
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Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
Target
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