Histone H2A antibody (pSer129)

Catalog No. ABIN7265302

This Rabbit Polyclonal antibody specifically detects Histone H2A in IHC. It exhibits reactivity toward Human and Rat.

Quick Overview for Histone H2A antibody (pSer129) (ABIN7265302)

Target: Histone H2A

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Histone H2A Antibody

Binding Specificity: pSer129

Characteristics: Phosphorylated antibody

Purification: Affinity purification

Immunogen: A phospho synthetic peptide corresponding to residues surrounding S129 of human Histone H2A.

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Histone H2A

Target: Histone H2A

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Gene ID: 851811

UniProt: P04911