CXCR5 antibody (AA 281-372)

Catalog No. ABIN701380

This Rabbit Polyclonal antibody specifically detects CXCR5 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Mouse and has been mentioned in 3+ publications.

Quick Overview for CXCR5 antibody (AA 281-372) (ABIN701380)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CXCR5 Antibody

Binding Specificity: AA 281-372

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CXCR5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CXCR5 antibody (ABIN701380)

Huang, Liu, Wang, Li: "Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173716, (2017) (PubMed).

Gong, Zhu, Pang, Ai, Gong, La, Ding: "Increased levels of CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5931-5941, (2017) (PubMed).

Target Details for CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Alternative Name: CXCR5/CD185

Background:

Synonyms: BLR1, CD185, MDR15, C-X-C chemokine receptor type 5, CXC-R5, CXCR-5, Burkitt lymphoma receptor 1, Monocyte-derived receptor 15, MDR-15, CXCR5

Background: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

Gene ID: 643

UniProt: P32302