TRAFs and NIK-Associated Protein (TNAP) antibody (APC)

Catalog No. ABIN7013887

The Mouse Monoclonal anti- antibody has been validated for FACS. It is suitable to detect in samples from Human, Dog, Goat, Monkey, Pig and Sheep.

Quick Overview for TRAFs and NIK-Associated Protein (TNAP) antibody (APC) (ABIN7013887)

Target: TRAFs and NIK-Associated Protein (TNAP)

Reactivity: Human, Dog, Goat, Monkey, Pig, Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: APC

Application: Flow Cytometry (FACS)

Clone: W8B2B10

Product Details

Purpose: Anti-TNAP APC

Specificity: The mouse monoclonal antibody W8B2B10 recognizes TNAP (tissue non-specific alkaline phosphatase), an ectoenzyme expressed mainly on embryonic stem cells, liver, bone, and kidney cells. This antibody is suitable for characterization of bone marrow-derived MSCs, iPSCs, and ESCs.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: WERI-RB-1 retinoblastoma cell line

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 2-5 μg/mL.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details

Target: TRAFs and NIK-Associated Protein (TNAP)

Alternative Name: TNAP

Background: Alkaline phosphatase, biomineralization associated,Tissue non-specific alkaline phosphatase (TNAP), also known as liver/bone/kidney alkaline phosphatase, or MSCA-1 (mesenchymal stem cell antigen 1) is a selective marker for the prospective isolation of bone marrow-derived mesenchymal stem cells and mesenchymal stem-like cells. It is expressed at high levels in liver, bone, kidney, or endometrium, as well as on embryonic stem cells (ESCs). TNAP also plays a role in bone mineralization. Mutations in TNAP gene are associated with hypercalcemia and skeletal defects (hypophosphatasia).,Tissue Non-specific Alkaline Phosphatase, MSCA-1, liver/bone/kidney alkaline phosphatase

Gene ID: 249

UniProt: P05186