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MCAM antibody (PerCP)

This anti-MCAM antibody is a Mouse Monoclonal antibody detecting MCAM in FACS. Suitable for Human, Mouse, Rabbit and Dog.
Catalog No. ABIN7013999

Quick Overview for MCAM antibody (PerCP) (ABIN7013999)

Target

See all MCAM Antibodies
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reactivity

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Human, Mouse, Rabbit, Dog

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This MCAM antibody is conjugated to PerCP

Application

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Flow Cytometry (FACS)

Clone

P1H12
  • Purpose

    Anti-Hu CD146 PerCP

    Specificity

    The mouse monoclonal antibody P1H12 recognizes an extracellular epitope of CD146, a 118 kDa transmembrane glycoprotein expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, melanoma cells, activated T cells and activated keratinocytes.

    No Cross-Reactivity

    Rat

    Purification

    Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    cultured human umbilical cells

    Isotype

    IgG1
  • Application Notes

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    Restrictions

    For Research Use only
  • Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    Alternative Name

    CD146

    Background

    Melanoma cell adhesion molecule,CD146, also known as MCAM (melanoma cell adhesion molecule) or MUC18, is a heavily glycosylated transmembrane glycoprotein with more than 50 % of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.,MelCAM, MCAM, MUC18

    Gene ID

    4162

    UniProt

    P43121
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