GPR77 antibody

Catalog No. ABIN7014008

The Mouse Monoclonal anti-GPR77 antibody (Clone 1D9-M12) (ABIN7014008) specifically detects GPR77 in WB and FACS. The antibody is reactive with Human and Non-Human Primate samples.

Quick Overview for GPR77 antibody (ABIN7014008)

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This GPR77 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 1D9-M12

Product Details anti-GPR77 Antibody

Purpose: Anti-Hu C5aR2 Purified

Characteristics: The mouse monoclonal antibody 1D9-M12 recognizes an extracellular epitope on C5aR2 (C5L2), a C5a complement receptor, which is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages.

Purification: Purified by protein-A affinity chromatography.

Immunogen: L1.2 cells transfected with human C5aR2

Isotype: IgG2a, kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 2-6 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for GPR77

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Alternative Name: C5aR2

Background: Complement component 5a receptor 2,C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.,C5L2, GPR77, GPF77

Gene ID: 27202

UniProt: Q9P296