FPR2 antibody (AA 51-150) (Biotin)

Catalog No. ABIN702177

This anti-FPR2 antibody is a Rabbit Polyclonal antibody detecting FPR2 in WB, ELISA. Suitable for Human, Mouse, Rat.

Quick Overview for FPR2 antibody (AA 51-150) (Biotin) (ABIN702177)

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPR2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-FPR2 Antibody (Biotin)

Binding Specificity: AA 51-150

Specificity: Possible cross-reactivity with FPR1

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FPRL1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Alternative Name: FPRL1/Lipoxin A4 receptor

Background:

Synonyms: ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II, N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, Lipoxin A4 receptor, LXA4 receptor, RFP, FPR2

Background: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Gene ID: 2358

UniProt: P25090