KPNB1 antibody (AA 165-270) (HRP)

Catalog No. ABIN702784

This Rabbit Polyclonal antibody specifically detects KPNB1 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for KPNB1 antibody (AA 165-270) (HRP) (ABIN702784)

Target: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KPNB1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-KPNB1 Antibody (HRP)

Binding Specificity: AA 165-270

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NTF97/KPNB1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KPNB1

Target: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Alternative Name: NTF97/KPNB1

Background:

Synonyms: IMB 1, IMB1, Impnb, Importin 90, Importin beta 1, Importin beta 1 subunit, IPOB, Karyopherin beta 1, Karyopherin beta 1 subunit, KPNB 1, KPNB1, MGC2155, MGC2156, MGC2157, NTF 97, NTF97, Nuclear factor p97, IMB1_HUMAN.

Background: NTF97 is involved in nuclear protein import, either by associating itself with an adapter protein (for example, importin-alpha subunit which binds to nuclear localization signals (NLS) in cargo substrates), or by acting autonomously as a nuclear transport receptor (serves as NLS receptor, docking of the importin/substrate complex to the nuclear pore complex).

Gene ID: 3837

Pathways: Protein targeting to Nucleus