MLLT10 antibody (AA 151-250) (HRP)

Catalog No. ABIN702799

This Rabbit Polyclonal antibody specifically detects MLLT10 in WB, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Rat.

Quick Overview for MLLT10 antibody (AA 151-250) (HRP) (ABIN702799)

Target: MLLT10 (Protein AF-10 (MLLT10))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLLT10 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MLLT10 Antibody (HRP)

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AF10/MLLT10

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MLLT10

Target: MLLT10 (Protein AF-10 (MLLT10))

Alternative Name: AF10

Background:

Synonyms: AF 10, AF10, AF10_HUMAN, ALL 1 fused gene from chromosome 10, ALL1 fused gene from chromosome 10, ALL1-fused gene from chromosome 10 protein, MLLT 10, MLLT10, Myeloid/lymphoid or mixed lineage leukemia trithorax homolog Drosophila translocated to 10, Myeloid/lymphoid or mixed lineage leukemia translocated to 10, Protein AF 10, Protein AF-10, Protein AF10, Type I AF10 protein.

Background: A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10,11)(p12,q23) with MLL/HRX. The result is a rogue activator protein.A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10,11)(p13,q14) with PICALM.

Gene ID: 8028