GALR3 antibody (2nd Extracellular Loop)

Catalog No. ABIN7886413

This Rabbit Polyclonal antibody specifically detects GALR3 in WB, IHC, IF, FACS and LCI. It exhibits reactivity toward Mouse.

Quick Overview for GALR3 antibody (2nd Extracellular Loop) (ABIN7886413)

Target: GALR3 (Galanin Receptor 3 (GALR3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Product Details anti-GALR3 Antibody

Binding Specificity: 2nd Extracellular Loop, AA 159-172

Purpose: A Rabbit Polyclonal Antibody to Galanin Receptor Type 3

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Rat,human - identical

Characteristics: Anti-GALR3 (extracellular) Antibody (ABIN7043182, ABIN7044400 and ABIN7044401) is a highly specific antibody directed against an epitope of the mouse Galanin receptor 3. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GALR3 from mouse, rat, and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogen: SYYGTVRYGALELC, corresponding to amino acid residues 159-172 of mouse Galanin receptor type 3

Isotype: IgG

Application Details

Application Notes:

WB: 1:200

FC: 2.5 μg per reaction

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Comment:

Negative Control: (ABIN7235481)

Blocking Peptide: (ABIN7235481)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Target Details for GALR3

Target: GALR3 (Galanin Receptor 3 (GALR3))

Alternative Name: GALR3

Background:

Synonyms: Galanin receptor type 3, GALNR3, GAL3R

Description: Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known receptors, the Galanin receptor type 1 (GALR1), Galanin receptor type 2 (GALR2) and Galanin receptor type 3 (GALR3). The Galanin receptors belong to the G-protein coupled receptor superfamily.1-4Based on mRNA, the GALR1 is predominantly distributed in the central nervous system, spinal cord and dorsal root ganglia while GALR2 is abundant in both central and peripheral nervous systems. GALR3 mRNA is distributed in peripheral tissues such as the heart, spleen, and testis. However, its expression in the brain is still controversial.4,5

Gene ID: 14429

NCBI Accession: NM_003614

UniProt: O88853

Pathways: cAMP Metabolic Process, Feeding Behaviour