Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

NPTXR antibody (Extracellular)

NPTXR Reactivity: Mouse WB, IHC, IF (cc), LCI Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7043370
  • Target See all NPTXR Antibodies
    NPTXR (Neuronal Pentraxin Receptor (NPTXR))
    Binding Specificity
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-176, Extracellular
    Reactivity
    • 13
    • 4
    • 3
    Mouse
    Host
    • 12
    • 2
    • 1
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    This NPTXR antibody is un-conjugated
    Application
    • 15
    • 13
    • 10
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
    Purpose
    A Rabbit Polyclonal Antibody to NPTXR (extracellular)
    Specificity
    Extracellular, C-terminus
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Rat - identical, human - 14 out of 15 amino acid residues identical
    Characteristics
    Anti-Neuronal Pentraxin Receptor (NPTXR)(extracellular) Antibody (ABIN7043370, ABIN7044746 and ABIN7044747)) is a highly specific antibody directed against an extracellular epitope of the mouse NPTXR. The antibody can be used in western blot and immunohistochemistry. It has been designed to recognize NPTXR from mouse, rat and human samples.
    Purification
    Affinity purified on immobilized antigen.
    Immunogen

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)RGLQDAGPRRDTMAD, corresponding to amino acid residues 162 - 176 of mouse NPTXR

    Isotype
    IgG
    Top Product
    Discover our top product NPTXR Primary Antibody
  • Application Notes

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:1200

    Application Dilutions Western blot wb: 1:400

    Comment

    Negative Control: BLP-NR193

    Blocking Peptide: BLP-NR193

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    0.2 mL double distilled water (DDW).
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4
    Storage
    4 °C,-20 °C
    Storage Comment

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • Target
    NPTXR (Neuronal Pentraxin Receptor (NPTXR))
    Alternative Name
    NPTXR (NPTXR Products)
    Background
    NPR, NPTXR,Neuronal Pentraxin Receptor (NPTXR) belongs to the Pentraxin superfamily of proteins (NP) that is characterized by a pentraxin domain at the C-terminal end. It is the only pentraxin family member anchored to the cell membrane by a putative N-terminal transmembrane domain, as opposed to the other two family members, Neuronal Pentraxin1 (NP1) and Neuronal Pentraxin 2 (NP2) that are secreted proteins. NPs can form homo pentamers and hetero pentamers via their pentraxin domains 1.NPTXR was first identified as the receptor for the snake venom toxin taipoxin and was later found to bind to AMPARs at excitatory synapses and play important, roles in the activity-dependent regulation of neural circuits via this binding activity 1.Lately, the levels of NPTXR protein in cerebrospinal fluid has been identified as a novel potential biomarker of Alzheimer's disease progression and could have important utility in assessing treatment success in clinical trials 2. In addition, NPTXR was identified as a molecule required for gastric cancer metastasis 3.

    Alternative names: NPR
    Gene ID
    73340
    NCBI Accession
    NM_014293
    UniProt
    Q99J85
You are here:
Support