KCNS2 antibody (Intracellular)

Catalog No. ABIN7043497

This Rabbit Polyclonal antibody specifically detects KCNS2 in WB. It exhibits reactivity toward Rat.

Quick Overview for KCNS2 antibody (Intracellular) (ABIN7043497)

Target: KCNS2 (Potassium Voltage-Gated Channel, Delayed-Rectifier, Subfamily S, Member 2 (KCNS2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNS2 Antibody

Binding Specificity: AA 430-445, Intracellular

Purpose: A Rabbit Polyclonal Antibody to KV9.2 Channel

Specificity: Intracellular, C-terminus

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Mouse,human - identical

Characteristics: Anti-KCNS2 (KV9.2) Antibody (ABIN7043497, ABIN7045034 and ABIN7045035) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize KV9.2 channel from human, rat, and mouse samples.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: CDFGDGMKEVPSVNLR, corresponding to amino acid residues 430-445 of rat KV9.2

Isotype: IgG

Application Details

Application Notes:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: 1:200

Comment:

Negative Control: (ABIN7236430)

Blocking Peptide: (ABIN7236430)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Storage: 4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for KCNS2

Target: KCNS2 (Potassium Voltage-Gated Channel, Delayed-Rectifier, Subfamily S, Member 2 (KCNS2))

Alternative Name: KCNS2

Background: Voltage-gated K+ channel subunit KV9.2,KV9.2 is a member of the electrically silent voltage-gated K+ (KV). Ten KV silent subunits have been identified: KV5.1, KV6.1-KV6.4, KV8.1, KV8.2, and KV9.1-KV9.3. KV9.2 modulates the activity of KV2.1 and KV2.2 channels1,2. KV9.2 structure includes six transmembrane segments: S1-S6, positive residues on S4, the K+ signature sequence GYG on the pore loop between S5 and S6, and cytoplasmic N and C termini2.High KV9.2 expression level can be found in the olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei, and cerebellum1.

Alternative names: KCNS2 (KV9.2), Voltage-gated K+ channel subunit KV9.2

Gene ID: 66022

NCBI Accession: NM_020697

UniProt: Q9ER26