KCNQ2 antibody (C-Term, Intracellular)

Catalog No. ABIN7043504

Product Details anti-KCNQ2 Antibody

Target: KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Binding Specificity: AA 578-593, C-Term, Intracellular

Reactivity: Rat, Human, Mouse

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This KCNQ2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity (Details): The antibody is specific for KCNQ2. It does not cross-react with KCNQ3 or other QKT proteins. There are at least 9 recognized splice variants of rat KCNQ2. This antibody recognizes all except splice variants B and G.

Characteristics: Guinea pig Anti-KCNQ2 Antibody (#), raised in guinea pigs, is a highly specific antibody directed against an epitope of the rat KV7.2 channel. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize KCNQ2 from mouse, rat, and human samples. The antigen used to immunize guinea pigs is the same as Anti-KCNQ2 Antibody (ABIN7043503, ABIN7044959 and ABIN7044960)) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation, etc.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RGPTITDKDRTKGPAE, corresponding to amino acid residues 578-593 of rat KCNQ2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for KCNQ2

Target: KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Alternative Name: KCNQ2 (KCNQ2 Products)

Background: Alternative names: KV7.2, Voltage-gated potassium channel QKT subfamily member 2, KvLQT2

Gene ID: 170848

NCBI Accession: NM_172109

UniProt: O88943