KCNQ2 antibody (AA 154-203)

Catalog No. ABIN6736411

This Rabbit Polyclonal antibody specifically detects KCNQ2 in WB, IHC and IHC (p). It exhibits reactivity toward Rat, Human, Mouse, Dog, Cow, Guinea Pig, Horse, Bat, Chicken and Monkey.

Quick Overview for KCNQ2 antibody (AA 154-203) (ABIN6736411)

Target: KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Reactivity: Rat, Human, Mouse, Dog, Cow, Guinea Pig, Horse, Bat, Chicken, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNQ2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KCNQ2 Antibody

Binding Specificity: AA 154-203

Specificity: Human KCNQ2

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Horse, Chicken (100%) Zebrafish (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa154-203 of human KCNQ2 (NP_004509). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Horse, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Lizard (100%), Zebrafish (92%), Gibbon, Rabbit, Pig, Armadillo (90%), Xenopus, Stickleback (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for KCNQ2

Target: KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Alternative Name: KCNQ2

Background: Name/Gene ID: KCNQ2
Subfamily: Potassium channel - KCNQ
Family: Ion Channel

Synonyms: KCNQ2, BFNS1, BFNC, EBN, EBN1, EIEE7, HNSPC, KQT2, KV7.2, KCNA11, KQT-like 2, ENB1, KVEBN1

Gene ID: 3785

NCBI Accession: NP_004509

UniProt: O43526