Synapsin III antibody (C-Term, Extracellular)

Catalog No. ABIN7886622

This Rabbit Polyclonal antibody specifically detects Synapsin III in WB, IHC and IF. It exhibits reactivity toward Rat.

Quick Overview for Synapsin III antibody (C-Term, Extracellular) (ABIN7886622)

Target: Synapsin III (SYN3)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synapsin III antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Synapsin III Antibody

Binding Specificity: AA 510-523, C-Term, Extracellular

Purpose: A Rabbit Polyclonal Antibody to Synapsin III

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Mouse,human - identical

Characteristics: Anti-Synapsin III (SYN3) Antibody (ABIN7043788, ABIN7044664 and ABIN7044665) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize Synapsin III from human, rat, and mouse samples.

Purification: Affinity purified on immobilized antigen.

Immunogen: (C)RPPVQGRSTSQQGE, corresponding to amino acid residues 510-523 of rat Synapsin III

Isotype: IgG

Application Details

Application Notes:

WB: 1:200-1:400

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:200

IP: The optimal concentration should be determined by the user

Comment:

Negative Control: (ABIN7237315)

Blocking Peptide: (ABIN7237315)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Target Details for Synapsin III

Target: Synapsin III (SYN3)

Alternative Name: SYN3

Background:

Synonyms: Synapsin-3

Description: Synapsin 3 (Syn3) belongs to the synapsin family of neuronal phosphoproteins, vesicle-associated proteins that includes two additional members: Synapsin I and Synapsin II. Alternative splicing of the genes results in at least ten variants with various levels of homology.Synapsins are involved in synaptogenesis, synaptic transmission and synaptic plasticity and are required for the formation and maintenance of the reserve and recycling pools of synaptic vesicles through association with the actin cytoskeleton. Several protein kinases, including PKA, calcium-calmodulin regulated protein kinases and the mitogen-activated protein kinase (MAPK) use synapsins as their substrates1-4.Syn3 plays an important role in several disorders, including bipolar disorder, schizophrenia and epilepsy1.

Gene ID: 29130

NCBI Accession: NM_001135774

UniProt: O70441