Recombinant Paxillin (LD4 Motif) (AA 260-278) antibody

Catalog No. ABIN7072304

The Rabbit Chimeric anti-Paxillin (LD4 Motif) antibody is suitable to detect Paxillin (LD4 Motif) in samples from Human. It has been validated for ELISA and WB.

Quick Overview for Recombinant Paxillin (LD4 Motif) (AA 260-278) antibody (ABIN7072304)

Target: Paxillin (LD4 Motif)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: LD4 sAB

Product Details

Binding Specificity: AA 260-278

Purpose: Anti-Paxillin (LD4 Motif) [LD4 sAB], Rabbit IgG, kappa

Specificity: The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: scFv

Purification: Protein A affinity purified

Immunogen: Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP, peptide sequence: WGGSATRELDELMASLSD.

Isotype: IgG kappa

Application Details

Application Notes: This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Comment:

This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details

Target: Paxillin (LD4 Motif)

Background: PXN

UniProt: P49023