Recombinant Paxillin (LD2 Motif) (AA 141-156) antibody

Catalog No. ABIN7072305

The Mouse Monoclonal anti-Paxillin (LD2 Motif) antibody (Clone LD2 sAB) (ABIN7072305) specifically detects Paxillin (LD2 Motif) in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant Paxillin (LD2 Motif) (AA 141-156) antibody (ABIN7072305)

Target: Paxillin (LD2 Motif)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: LD2 sAB

Product Details

Binding Specificity: AA 141-156

Purpose: Anti-Paxillin (LD2 Motif) [LD2 sAB], Mouse IgG1, kappa

Specificity: The antibody binds specifically to the LD-2 motif of human paxillin with a Kd of 24 nM.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: scFv

Purification: Protein A affinity purified

Immunogen: Peptide corresponding to paxillin-LD2 motif (residues 141-156) fused to MBP, peptide sequence: NLSELDRLLLELNAVQHNP.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody binds to the LD2-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Comment:

This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details

Target: Paxillin (LD2 Motif)

Background: PXN

UniProt: P49023