Recombinant Muscle Acetylcholine Receptor antibody
Quick Overview for Recombinant Muscle Acetylcholine Receptor antibody (ABIN7072312)
Target
Antibody Type
Reactivity
Host
Clonality
Application
Clone
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Purpose
- Anti-Human Muscle Acetylcholine Receptor [mAb 192], Rat IgG2b, kappa
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Specificity
- The antibody binds to human muscle AChR with a Kd of 10 pM, to mouse muscle AChR with a Kd of 50 pM, and to rat muscle AChR with a Kd of 646 nM.
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Cross-Reactivity
- Mouse, Rat
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Characteristics
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Original Species of Ab: Rat
Original Format of Ab: IgG2b
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Purification
- Protein A affinity purified
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Immunogen
- Human muscle AChR.
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Isotype
- IgG2b kappa
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Application Notes
- This antibody binds to the human muscle Acetylcholine receptor, which is a ligand-gated ion channel, transducing an action potential into the muscle cells. The antibody binds to the main immunogenic region (MIR) and prevents ligand-binding.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Muscle Acetylcholine Receptor
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Background
- AChR
Target
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